Rak na kosteh - osteo sarcoma - kje dobiti marihuano ( legalno ) in ostala vprašanja.

imagodei je 11. apr 2011 ob 15:02 izjavil:

Trgovine ne poznam, ampak sem 100% prepričan, da tam ne prodajajo nobenih semen. Prodaja marihuaninih semen bi ziher padla pod neupravičeno proizvodnjo in promet s prepovedanimi substancami in takšno trgovino bi gladko zaprli, odgovorne pa kazensko preganjali.

Če se pa slučajno kaj prodaja "pod pultom", je pa druga reč. Ampak hudo dvomim, da kar vsakemu "Average Joeu", ki jih pobara, ponudijo robo.

para! je 15. apr 2011 ob 10:50 izjavil:

Prepoved gojenja marihuane še ni dovolj dober razlog za prepoved semen iz katerih marihuana zraste. Ne vem sicer kakšno uporabo bi semena poleg gojenja še lahko imela, ampak nedvomno se jih najde.

If Price's research pans out, a few years from now it may be possible to map out a brain tumor in 3-D, then tailor the approach for focused ultrasound-mediated drug delivery depending on the position of the tumor.

Her research began a decade ago when she realized that ultrasound enhances drug release from microscopic nanoparticles called polymeric micelles.

"When you encapsulate a drug in nanoparticles, you can target it to the tumor," Rapoport said. "This is because the blood vessels in tumors are much more permeable than in normal tissues. This is the Achilles heel of the tumor, which allows drug-loaded nanoparticles to get through into tumor tissue without penetrating into normal tissue. Then we focus ultrasound in the tumor to release the drug from nanoparticles."

But there are so many problems treating pancreatic cancer. The disease is often asymptomatic and discovered too late. And drug diffusion over the tumor is challenging. Plus, Rapoport said, it is common for pancreatic cancer cells to quickly become resistant to drug treatment.

However, Rapoport has found a potential solution, and if she's successful, perhaps, one day, inoperable pancreatic tumors could be shrunken and made operable. "We inject paclitaxil loaded nanodroplets and they accumulate in the tumor," Rapoport explained. "The accumulation is enhanced by focused ultrasound, which increases the gaps between endothelial (blood vessel wall) cells. When we sonicate these nanodroplets (irradiate them with ultrasound) they convert into microbubbles and when they convert they release their drug load." Ultrasound is known to enhance diffusion and help to overcome all biological barriers for a drug to hit its target inside cancerous cells.

In past experiments on mice with pancreatic tumors, she discovered that large tumors regress significantly during treatment with ultrasound-mediated drug delivery under MRI guidance while smaller tumors die and don't appear to recur after completion of treatment.

SV40 is believed to suppress the transcriptional properties of the tumor-suppressing p53 in humans through the SV40 Large T-antigen and SV40 Small T-antigen. p53 is responsible for initiating regulated cell death ("apoptosis"), or cell cycle arrest when a cell is damaged. A mutated p53 gene may contribute to uncontrolled cellular proliferation, leading to a tumor.

We found SV40 large T antigen sequences in all brain tumor types investigated. High frequencies were found in low-grade astrocytomas, anaplastic astrocytomas and secondary glioblastomas derived thereof (13/22, 59%) while somewhat lower frequencies were found in gemistocytic astrocytomas (9/28, 32%) and oligodendrogliomas (3/12, 25%). Primary glioblastomas, giant cell glioblastomas, and gliosarcomas, which clinically develop de novo, contained SV40 sequences in 11-25% of cases. Presence of viral DNA was also observed in pediatric brain tumors, including ependymomas (9/16, 56%), choroid plexus papillomas (6/16, 38%), and medulloblastomas (5/17, 29%).

Prof. dr. Mario Poljak pravi, da >>noben rakotvoren dejavnik, ki jih poznamo v medicini, nima z rakom, ki ga povzroča, tako močne povezave kot HPV z rakom materničnega vratu.<<

Cabbage consumption was associated with a statistically significant lower risk of pancreatic cancer (>=1 serving/wk versus never consumption: HR, 0.62; 95% CI, 0.39-0.99).

In a large epidemiologic study, Mayo Clinic researchers have found that using aspirin as infrequently as once a month substantially reduced risk of developing pancreatic cancer.

Results showed that people who took aspirin at least one day during a month had a 26 percent decreased risk of pancreatic cancer compared to those who did not take aspirin regularly. The effect was also found for those who took low-dose aspirin for heart disease prevention at 35 percent lower risk, according to Tan.

Profesorja z univerze v Tel Avivu Jona Keisari in Jicak Kelson naj bi tako kmalu začela s kliničnimi poskusi z radioaktivnim vsadkom, ki bo v notranjosti tumorja oddajal alfa žarke. V nasprotju z običajno terapijo obsevanja, s katero telo obsevajo z gama žarki od zunaj, naj bi se alfa žarki razpršili znotraj tumorja, se nato širili naprej, na koncu pa razkrojili.
...
Tovrstna terapija naj bi trajala deset dni, za seboj pa naj bi pustila samo neradioaktivno in nestrupeno količino svinca. Žični vsadek vsadijo v tumor s pomočjo podkožne igle, ki v telesu brez škode razpade. Doslej so omenjeno metodo preizkušali na miših, klinične poskuse pa naj bi začeli kmalu opravljati v bolnišnici Beilinson v bližini Tel Aviva, še poroča AFP.

RESULTS: The insertion of a single DART wire into the center of 6- to 7-mm tumors had a pronounced retardation effect on tumor growth, leading to a significant inhibition of 49% (LL2) and 93% (A427) in tumor development and prolongations of 48% (LL2) in life expectancy. In the human model, more than 80% of the treated tumors disappeared or shrunk.

Pyr0Beast je 24. jan 2012 ob 12:07 izjavil:

Sej nekako podobna zadeva je s klasično terapijo. Nič ne obljubljajo, pa folk še vedno umira na koncu.

Pyr0Beast je 3. feb 2012 ob 23:00 izjavil:

Ne vem če imamo kje v sloveniji Evidence-based kemoterapijo pri kateri se preverja output zdravih ljudi

Brane22 je 13. jul 2012 ob 15:35 izjavil:

Update:

Dva tedna nazaj sem si med poskusom hujšanja s tekom zjebal mišično kito tik pod kolenom. Stvar je začela peč u 3PM ravno tam, kjer se kita prime kosti.

Bolečina je bila precej zajebana, predvsem pa kronična. Stalno je s tabo, tud spat ne moreš. Bolečina pa je tistega zajebanega tipa, kot da te je delček sekunde prej nekdo užgal s kladivom v kost in sedaj stvar vibrira tako, kot da bo zaradi tega počila.

V glavnem, trpel sem jo par dni, nato ap se spomnil, da mi je za fotrom ostal še vaporizator in malo marihuane v njem.

Tista stvar je bila že precj izrabljena in učinek je bil omejen. Stvar me je še vedno bolela, le da sem ob tem skorajda umiral od smeha.

Naslednji dan sem našel v vrečki še zadnje ostanke- še mogoče pol grama neuporabljene, čeprav mogoče že plesnive robe in probal to.

Rezultat je bil zanimiv. Po nekem času se je začelo tosto znanjp sčemenje v mišicah, kateremu sem se prepustil in dovolil da mi stvar proži posamezne mišice kar je bilo čutiti nekako kot v tistih filmskih "Las Vegas" neonskih reklamah, kjer dosegajo kao animacijo s prižiganjem in ugašanjem posameznih neonk.

Bilo je neugodno v začetku le takrat ko se je sprožila boleča mišica, potem pa je neugodje počasi izginilo ( v roku par minut, mogoče 5, pa še takrat ni bilo alarmantno), potem pa je... bolečina IZGINILA. Skorajda hipoma, ajde v roku recimo 15 sekund.

Zanimivo je, da ni bilo neke omame, ki bi omrtvičila živce ali kaj takega. Le bolečina je padla pod nek,s edaj premaknjen prag trigeriranja.

Čez čas se mi je zluštal spanec in zaspal sem trdno. Ko sem se zbudil, bolečine ni bilo nazaj še nekaj ur, pa še takrat se je vrnila polagoma.

Če ne bi bilo zakonskih jebad, bi par gramov tegale imel definitivno kje v vrečki na hladnem za take in podobne slučaje.

Brane22 je 13. jul 2012 ob 16:00 izjavil:

Aja, pa še ena stvar.
Stalna bolečina ti naredi nekakšen "temen oblak" v glavi, ki se ga niti ne zavedaš.

Zaveš se pa njegove odsotnosti tisti trenutek, ko se zbudiš brez bolečine. Dejanjsko drugače gledaš na stvari okrog sebe.